Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987410 | 0.96 | ESR2 (0.34) | ESR2ESR1 | |
| SCHEMBL803460 | 0.84 | ESR2 (0.31) | ESR2 | |
| SCHEMBL8932574 | 0.81 | PSMB5 (0.32) | — | |
| SCHEMBL13760084 | 0.81 | ESR2 (0.31) | ESR2 | |
| SCHEMBL13760086 | 0.81 | TRPV3 (0.31) | ESR2 | |
| SCHEMBL803461 | 0.80 | — | — | |
| SCHEMBL4549777 | 0.80 | SCN9A (0.33) | — | |
| SCHEMBL15725306 | 0.79 | ESR2 (0.44) | ESR2WDR5 | |
| SCHEMBL12662767 | 0.79 | ESR2 (0.44) | ESR2WDR5 | |
| SCHEMBL17359301 | 0.78 | ALOX5AP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114310-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20090324853-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| US-20080308768-A1 | Liquid Crystalline Medium | MERCK PATENT GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
| US-7371437-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |