SCHEMBL10067478

SCHEMBL10067478

CCN(CC)Cn1c2ccccc2c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
NPY1R P25929 1/20 0.57
NPY2R P49146 1/20 0.57
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
TSPO P30536 2/20 0.51
SLC6A4 P31645 2/20 0.49
SLC6A2 P23975 1/20 0.49
HRH1 P35367 1/20 0.49
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
RAD52 P43351 1/20 0.46
RAB9A P51151 1/20 0.46
SMARCA2 P51531 1/20 0.46
HIF1A Q16665 1/20 0.45
CYP19A1 P11511 1/20 0.45
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26710134 0.87 TSHR (0.47) TSHRNPY1RNPY2RCYP1A2CYP2C19
SCHEMBL26710136 0.82 TSHR (0.46) TSHRNPY1RNPY2RCYP1A2CYP2C19
SCHEMBL26710133 0.82 TSHR (0.42) TSHRNPY1RNPY2RCYP1A2CYP2C19
SCHEMBL2334457 0.80 POLB (0.63) TSHRNPY1RNPY2RCYP1A2CYP2C19
SCHEMBL14328056 0.78 CYP1A2 (0.56) TSHRNPY1RNPY2RCYP1A2CYP2C19
SCHEMBL19284181 0.78 MAPT (0.42) TSHRNPY1RNPY2RTSPOSLC6A4
SCHEMBL4780222 0.77 SLC6A4 (0.72) TSHRNPY1RNPY2RSLC6A4SLC6A2
SCHEMBL13305190 0.76 SLC6A4 (0.80) TSHRNPY1RNPY2RSLC6A4SLC6A2
SCHEMBL151563 0.75 ALDH1A1 (0.75) TSHRCYP1A2CYP2C19ALDH1A1NPC1
SCHEMBL29360167 0.75 ALDH1A1 (0.75) TSHRCYP1A2CYP2C19ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997711-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-20170213969-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-27 US disclosed
US-20170213977-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-27 US disclosed
US-20160197277-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160197277-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT CHRM1, L1CAM, ESR1 TSHR 4113/4885NPY1R 2588/4885NPY2R 3543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.