⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoleucine SCHEMBL1255583 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL6682941 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL8868 | 1.00 | — | — | |
| Isoleucine SCHEMBL1147268 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL8869 | 1.00 | — | — | |
| Isoleucine SCHEMBL21335 | 1.00 | — | — | |
| Isoleucine SCHEMBL2783498 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL5973421 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL288159 | 1.00 | — | — | |
| Isoleucine SCHEMBL8045737 | 1.00 | SLC7A5 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025949-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | TREVENA, INC. | 2024-01-25 | — | — | US | disclosed |
| EP-4225788-A2 | ANTI-NGF ANTIBODIES AND METHODS OF USE THEREOF | Zoetis Services LLC (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-115850240-A | Synthetic method of drug Olutascinonide for treating acute myeloid leukemia | 北京康立生医药技术开发有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115850240-A | Synthetic method of drug Olutascinonide for treating acute myeloid leukemia | 北京康立生医药技术开发有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113493487-B | Compound and composition and application thereof in preparation of product for promoting proliferation of probiotics and/or inhibiting growth of harmful bacteria | 深圳海创生物科技有限公司 | 2022-05-17 | — | — | CN | disclosed |
| WO-2022076712-A2 | ANTI-NGF ANTIBODIES AND METHODS OF USE THEREOF | ZOETIS SERVICES LLC (US) | 2022-04-14 | — | — | WO | disclosed |
| US-20220106391-A1 | ANTI-NGF ANTIBODIES AND METHODS OF USE THEREOF | ZOETIS SERVICES LLC | 2022-04-07 | — | — | US | disclosed |
| US-20210324005-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | TREVENA, INC. | 2021-10-21 | — | — | US | disclosed |
| CN-113493487-A | Compound and composition and application thereof in preparation of product for promoting proliferation of probiotics and/or inhibiting growth of harmful bacteria | 深圳海创生物科技有限公司 | 2021-10-12 | — | — | CN | disclosed |
| US-10738151-B2 | Biorenewable, water-degradable polymers and co-polymers | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| US-9090667-B2 | Cyclic peptide from Nonomuraea sp., process for the production thereof, and pharmaceutical composition for the prevention or treatment of mycobacteria related disease comprising the same | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2015-07-28 | — | — | US | disclosed |
| US-20140357562-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2014-12-04 | — | — | US | disclosed |
| US-8809260-B2 | β-arrestin effectors and compositions and methods of use thereof | TREVENA, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20140142031-A1 | CYCLIC PEPTIDE FROM NONOMURAEA SP., PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF MYCOBACTERIA RELATED DISEASE COMPRISING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2014-05-22 | — | — | US | disclosed |
| US-20140127155-A1 | Smac mimetic dimers and trimers useful as anti-cancer agents | JOYANT PHARMACEUTICALS, INC (US) | 2014-05-08 | — | — | US | disclosed |
| WO-2013165554-A1 | METHODS AND COMPOSITIONS FOR MODULATING G-ALPHA-Q SIGNALING | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-11-07 | — | — | WO | disclosed |
| US-20130274176-A1 | BETA-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-8119653-B2 | Belactosin derivatives as therapeutic agents/biological probes and their synthesis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110092557-A1 | Neuraminidase Inhibitors And Compositions And Methods Related Thereto | INFLUMEDIX INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-20090042922-A1 | NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2009-02-12 | — | — | US | disclosed |