Isoleucine

Isoleucine

SCHEMBL1255583

CC[C@H](C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.55
DPP4 P27487 10/20 0.48
DPP8 Q6V1X1 6/20 0.48
DPP9 Q86TI2 6/20 0.48
DPP7 Q9UHL4 5/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoleucine SCHEMBL2783498 1.00 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9DPP7
Isoleucine SCHEMBL20340795 1.00
Isoleucine SCHEMBL5973421 1.00 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9DPP7
Isoleucine SCHEMBL8043620 1.00 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9DPP7
Isoleucine SCHEMBL1255582 1.00 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9DPP7
Isoleucine SCHEMBL1147268 1.00 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9DPP7
Isoleucine SCHEMBL8045737 1.00 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9DPP7
Isoleucine SCHEMBL8868 1.00
Isoleucine SCHEMBL8186739 1.00 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9DPP7
Isoleucine SCHEMBL8869 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116064644-A SbAGO1b protein and application of coding gene thereof in regulation and control of plant insect resistance 中国农业科学院生物技术研究所 2023-05-05 CN claimed
WO-2023001245-A1 CONJUGATE OF CELL-PENETRATING PEPTIDE AND MELPHALAN, AND PREPARATION CONTAINING CONJUGATE 奥朗生物医药有限公司 2023-01-26 WO claimed
CN-101781325-A Gallium salicylaldehyde amino acid Schiff base quaternary coordination compound, preparation method and application thereof UNIV BEIJING NORMAL 2010-07-21 CN claimed
CN-116064644-B SbAGO1b protein and application of coding gene thereof in regulation and control of plant insect resistance 中国农业科学院生物技术研究所 2023-10-10 CN disclosed
CN-111278848-B TALE RVD for specifically recognizing methylation modified DNA base and application thereof 北京大学 2023-06-27 CN disclosed
CN-116064644-A SbAGO1b protein and application of coding gene thereof in regulation and control of plant insect resistance 中国农业科学院生物技术研究所 2023-05-05 CN disclosed
WO-2023001245-A1 CONJUGATE OF CELL-PENETRATING PEPTIDE AND MELPHALAN, AND PREPARATION CONTAINING CONJUGATE 奥朗生物医药有限公司 2023-01-26 WO disclosed
CN-113180248-A Composition with effects of dispelling effects of alcohol and protecting liver and preparation method and health-care product thereof 海南蛛王生物科技有限公司 2021-07-30 CN disclosed
CN-109384833-B TALE RVD for specifically recognizing methylated modified DNA base and application thereof 北京大学 2021-04-27 CN disclosed
CN-111278848-A TALE RVD for specifically recognizing methylated modified DNA base and application thereof 北京大学 2020-06-12 CN disclosed
CN-110150760-A A kind of aerosol generation system 钟术光 2019-08-23 CN disclosed
CN-101781325-A Gallium salicylaldehyde amino acid Schiff base quaternary coordination compound, preparation method and application thereof UNIV BEIJING NORMAL 2010-07-21 CN disclosed
CN-1325063-C L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2007-07-11 CN disclosed
EP-1751283-A1 FED-BATCH FERMENTATION PROCESS AND CULTURE MEDIUM FOR THE PRODUCTION OF PLASMID DNA IN E.COLI ON A MANUFACTURING SCALE Boehringer Ingelheim Austria GmbH (AT) 2007-02-14 EP disclosed
CN-1709282-A L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2005-12-21 CN disclosed
WO-2005097990-A1 FED-BATCH FERMENTATION PROCESS AND CULTURE MEDIUM FOR THE PRODUCTION OF PLASMID DNA IN E.COLI ON A MANUFACTURING SCALE BOEHRINGER INGELHEIM AUSTRIA GMBH (AT) 2005-10-20 WO disclosed
US-6091002-A GENERATING A TRANSFORMED PLANT BY INSERTION NUCLEOTIDE SEQUENCE INTO CELLS, ISOLATING TRANSFORMED CELLS, REGENERATING THE TRANSFORMED CELLS TO FORM TRANSFORMED PLANTS, DETECTING CELLS THAT PRODUCE POLYMER MONSANTO COMPANY (US) 2000-07-18 US disclosed
US-5959179-A Method for transforming soybeans MONSANTO COMPANY (US) 1999-09-28 US disclosed
US-5958745-A ISOLATED ALCALIGENES EUTROPHUS BKTB, BETA-KETOTHIOLASE; FOR GENETICALLY ENGINEERED PRODUCTION OF POLYESTER COPOLYMERS USEFUL AS BIODEGRADABLE PLASTICS AND ELASTOMERS MONSANTO COMPANY (US) 1999-09-28 US disclosed
US-5942660-A A PLANT HAVING A GENOME OF RECOMBINANT DNA ENCODING INCREASED LEVELS OF BETA-KETOTHIOLASE, A BETA-KETOACYL-COENZYME A REDUCTASE, A POLYHYDROXYALKANATE SYMTHASE AND A DEREGULATED THREONINE DEAMINASE MONSANTO COMPANY (US) 1999-08-24 US disclosed