Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17686901 | 0.79 | ABAT (0.31) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL17695754 | 0.79 | ABAT (0.31) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL18414293 | 0.72 | EPHX1 (0.33) | TDP1 | |
| SCHEMBL16247862 | 0.72 | — | — | |
| SCHEMBL21162105 | 0.67 | — | — | |
| SCHEMBL2535697 | 0.65 | — | — | |
| SCHEMBL17366013 | 0.65 | — | — | |
| SCHEMBL6278266 | 0.65 | — | — | |
| SCHEMBL28180466 | 0.63 | — | — | |
| SCHEMBL11579330 | 0.61 | POLB (0.36) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088668-A1 | THINNING AGENT | TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088668-A1 | THINNING AGENT | NAT1, MAP2, AANAT | TSHR 2898/4885MAPK1 1708/4885HSD17B10 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.