Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068417 | 0.83 | ATM (0.44) | ATMNPFFR1NPFFR2SYKSIGMAR1 | |
| SCHEMBL13244198 | 0.79 | ATM (0.59) | ATMNPFFR1NPFFR2CYP2D6CYP3A4 | |
| SCHEMBL272157 | 0.76 | ATM (0.64) | ATMCYP3A4SYKSIGMAR1ACE | |
| SCHEMBL30220891 | 0.75 | NPFFR1 (0.46) | ATMNPFFR1NPFFR2ACEKMT2A | |
| SCHEMBL13738215 | 0.73 | NPFFR1 (0.57) | NPFFR1NPFFR2CYP2D6CYP3A4SIGMAR1 | |
| SCHEMBL555251 | 0.73 | KMT2A (0.62) | NPFFR1NPFFR2SIGMAR1KMT2AL3MBTL1 | |
| SCHEMBL1031172 | 0.73 | NPFFR1 (0.53) | NPFFR1NPFFR2CYP2D6CYP3A4SIGMAR1 | |
| SCHEMBL1361202 | 0.72 | KMT2A (0.62) | ATMCYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15809950 | 0.72 | KMT2A (0.62) | ATMCYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1504753 | 0.72 | POLB (0.47) | ATMNPFFR1NPFFR2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105567-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING SPA (IT) | 2012-01-31 | — | — | US | disclosed |
| US-20100069628-A1 | Multidentate AZA Ligands Able to Complex Metal Ions And The Use Thereof In Diagnostics And Therapy | BRACCO IMAGING S.P.A (IT) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069628-A1 | Multidentate AZA Ligands Able to Complex Metal Ions And The Use Thereof In Diagnostics And Therapy | CD99, MB, HBZ | ATM 2372/4885NPFFR1 2800/4885NPFFR2 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.