SCHEMBL10068532

SCHEMBL10068532

CCC(OCc1ccc(C)cc1)OCc1ccc(C(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
NFE2L2 Q16236 1/20 0.42
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
AGXT P21549 2/20 0.41
FFAR1 O14842 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
CNR2 P34972 2/20 0.38
CNR1 P21554 1/20 0.37
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10068089 0.93 IDO1 (0.57) IDO1NFE2L2RXRARXRBRAB9A
SCHEMBL13177113 0.79 NPC1 (0.40) AGXTFFAR1RAB9ANPC1L3MBTL1
SCHEMBL14196458 0.76 IDO1 (0.44) IDO1ACHERXRARXRBRAB9A
SCHEMBL4314773 0.76 TSHR (0.41) IDO1AGXTRAB9AL3MBTL1GAA
SCHEMBL9070613 0.76 AGXT (0.48) IDO1AGXTFFAR1RAB9ANPC1
SCHEMBL260335 0.75 IDO1 (0.63) IDO1NFE2L2RXRARXRBRAB9A
SCHEMBL9946062 0.75 RXRA (0.64) IDO1FFAR1RXRARXRBRAB9A
SCHEMBL9946032 0.75 RXRA (0.64) IDO1FFAR1RXRARXRBRAB9A
SCHEMBL407132 0.73 AGXT (0.54) IDO1ACHEAGXTFFAR1RAB9A
SCHEMBL6546912 0.73 BCHE (0.51) IDO1NFE2L2BCHEACHECNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092720-B2 Polymer-supported metal complex catalyst NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2012-01-10 US disclosed