Phyllocladene

Phyllocladene

SCHEMBL1006869

C=C1C[C@]23CC[C@H]4C(C)(C)CCC[C@]4(C)[C@H]2CC[C@@H]1C3

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.72
HSD11B2 P80365 1/20 0.72
PTPN1 P18031 5/20 0.69
BCHE P06276 2/20 0.45
ACHE P22303 1/20 0.45
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTPN2 P17706 2/20 0.38
RPS6KA5 O75582 2/20 0.36
MAPKAPK2 P49137 2/20 0.36
F10 P00742 1/20 0.34
CDC25B P30305 1/20 0.34
IDO1 P14902 1/20 0.34
ATM Q13315 1/20 0.34
PNLIP P16233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phyllocladene SCHEMBL29437839 1.00 HSD11B1 (0.72) HSD11B1HSD11B2PTPN1BCHEACHE
Phyllocladene SCHEMBL156928 1.00 HSD11B1 (0.72) HSD11B1HSD11B2PTPN1BCHEACHE
Phyllocladene SCHEMBL1006868 1.00 HSD11B1 (0.72) HSD11B1HSD11B2PTPN1BCHEACHE
Phyllocladene SCHEMBL29388334 1.00 HSD11B1 (0.72) HSD11B1HSD11B2PTPN1BCHEACHE
Phyllocladene SCHEMBL16414456 0.88 PTPN1 (0.65) HSD11B1HSD11B2PTPN1BCHEACHE
Phyllocladene SCHEMBL20538769 0.88 PTPN1 (0.65) HSD11B1HSD11B2PTPN1BCHEACHE
SCHEMBL267551 0.84 HSD11B1 (1.00) HSD11B1HSD11B2PTPN1BCHEACHE
SCHEMBL20738425 0.84 HSD11B1 (1.00) HSD11B1HSD11B2PTPN1BCHEACHE
SCHEMBL3491660 0.84 HSD11B1 (1.00) HSD11B1HSD11B2PTPN1BCHEACHE
SCHEMBL21331728 0.84 HSD11B1 (1.00) HSD11B1HSD11B2PTPN1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724566-A1 ENGINEERING HUMAN SKIN MICROBES TO PRODUCE MOSQUITO REPELLENT TERPENES Massachusetts Institute of Technology (US) 2026-04-15 EP claimed
WO-2024253742-A1 ENGINEERING HUMAN SKIN MICROBES TO PRODUCE MOSQUITO REPELLENT TERPENES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-12-12 WO claimed
EP-4208041-A1 COMPOSITIONS ISOLATED FROM DATE PALM TREE The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Institute) (IL) 2023-07-12 EP claimed
CN-116236539-A Complex extract of cheilobium axillarm, composition containing the same and application thereof 赖立民 2023-06-09 CN claimed
CN-107522680-A South America amphibious crab chrysanthemum antineoplastic extract and its production and use 海南师范大学 2017-12-29 CN claimed
CN-104003998-B Oridonin 14-0-sustituted nitrogen mustard derivatives, and preparation method and application thereof 中国药科大学 2017-01-11 CN claimed
CN-104730031-A Method for determining chemical components of rosin by using near infrared spectrum technology RES INST SUBTROPICAL FORESTRY CAF 2015-06-24 CN claimed
EP-4724566-A1 ENGINEERING HUMAN SKIN MICROBES TO PRODUCE MOSQUITO REPELLENT TERPENES Massachusetts Institute of Technology (US) 2026-04-15 EP disclosed
WO-2024253742-A1 ENGINEERING HUMAN SKIN MICROBES TO PRODUCE MOSQUITO REPELLENT TERPENES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-12-12 WO disclosed
US-20230263182-A1 COMPOSITIONS ISOLATED FROM DATE PALM TREE THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (IL) 2023-08-24 US disclosed
EP-4208041-A1 COMPOSITIONS ISOLATED FROM DATE PALM TREE The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Institute) (IL) 2023-07-12 EP disclosed
CN-116322368-A Composition isolated from date palm 以色列国家农业部·农村发展农业研究组织·沃尔卡尼机构 2023-06-23 CN disclosed
CN-116236539-A Complex extract of cheilobium axillarm, composition containing the same and application thereof 赖立民 2023-06-09 CN disclosed
US-20120157311-A1 HERBICIDE COMPOSITION AND WEED CONTROL METHOD SDS BIOTECH K.K. (JP) 2012-06-21 US disclosed
WO-2011048617-A2 EXTRACTS, FRACTIONS AND COMPOSITIONS COMPRISING ACETOGENINS AND THEIR APPLICATIONS LAILA NUTRACEUTICALS (IN) 2011-04-28 WO disclosed
CN-101977511-A Herbicide composition and weed control method SDS BIOTECH CORP 2011-02-16 CN disclosed
US-20110028322-A1 HERBICIDE COMPOSITION AND WEED CONTROL METHOD SDS BIOTECH K.K. (JP) 2011-02-03 US disclosed
EP-2269462-A1 HERBICIDE COMPOSITION AND WEED CONTROL METHOD Sds Biotech K.k. (JP) 2011-01-05 EP disclosed
CN-101538576-A Gene for generating related diterpene synthase together with tanshinone type compound as well as encoding product and application thereof INST OF CHINESE MEDICINE CHINA 2009-09-23 CN disclosed
CN-1294486-A I (stevia rebaudiana) with altered steviol glycoside compsn. AGRICULTURE & AGRICULTURAL FOO (CA) 2001-05-09 CN disclosed