Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069662 | 0.92 | ALDH1A1 (0.49) | KDM4ECYP19A1ALDH1A1NPC1PLA2G1B | |
| SCHEMBL10070190 | 0.85 | ALDH1A1 (0.65) | KDM4ECYP19A1ALDH1A1NPC1RAB9A | |
| SCHEMBL10069659 | 0.85 | ALDH1A1 (0.44) | KDM4ECYP19A1ALDH1A1NPC1PLA2G1B | |
| SCHEMBL10069663 | 0.83 | TNKS2 (0.47) | KDM4ECYP19A1ALDH1A1NPC1PLA2G1B | |
| SCHEMBL17461556 | 0.83 | ALDH1A1 (0.42) | KDM4ECYP19A1ALDH1A1NPC1PLA2G1B | |
| SCHEMBL6146090 | 0.80 | KDM4E (0.59) | KDM4ECYP19A1ALDH1A1EEF2KALDH2 | |
| SCHEMBL12121778 | 0.80 | KDM4E (0.59) | KDM4ECYP19A1ALDH1A1EEF2KALDH2 | |
| SCHEMBL6146093 | 0.80 | KDM4E (0.59) | KDM4ECYP19A1ALDH1A1EEF2KALDH2 | |
| SCHEMBL570789 | 0.79 | ALDH1A1 (0.55) | KDM4ECYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL10069664 | 0.79 | KDM4E (0.40) | KDM4ECYP19A1ALDH1A1NPC1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012016619-A1 | PHENETHYL, PHENETHYLENE, PHENETHYNE AND INDANONE DERIVATES IN COSMETIC FORMULATIONS, ESPECIALLY FOR USE IN SKIN AGEING PROCESSES | MERCK PATENT GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |