SCHEMBL10069752

SCHEMBL10069752

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nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDA P32320 14/20 0.59
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10069558 1.00 CDA (0.59) CDAMAPT
SCHEMBL13828301 1.00 CDA (0.59) CDAMAPT
SCHEMBL12338470 1.00 CDA (0.59) CDAMAPT
SCHEMBL13828333 1.00 CDA (0.59) CDAMAPT
SCHEMBL10070124 1.00 CDA (0.59) CDAMAPT
SCHEMBL12338454 1.00 CDA (0.59) CDAMAPT
SCHEMBL10069552 1.00 CDA (0.59) CDAMAPT
SCHEMBL12338462 1.00 CDA (0.59) CDAMAPT
SCHEMBL10069547 1.00 CDA (0.59) CDAMAPT
SCHEMBL13828342 1.00 CDA (0.59) CDAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9567363-B2 Certain compounds, compositions and methods OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-02-14 US disclosed
US-9567363-B2 Certain compounds, compositions and methods OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-02-14 US disclosed
US-20150210730-A1 CERTAIN COMPOUNDS, COMPOSITIONS AND METHODS TAIHO PHARMACEUTICAL CO., LTD. (JP) 2015-07-30 US disclosed
US-20150210730-A1 CERTAIN COMPOUNDS, COMPOSITIONS AND METHODS TAIHO PHARMACEUTICAL CO., LTD. (JP) 2015-07-30 US disclosed
US-8951987-B2 Certain compounds, compositions and methods OTSUKA PHARMACEUTICALS CO., LTD. (JP) 2015-02-10 US disclosed
US-8951987-B2 Certain compounds, compositions and methods OTSUKA PHARMACEUTICALS CO., LTD. (JP) 2015-02-10 US disclosed
US-20140186335-A1 Certain Compounds, Compositions and Methods EISAI INC. (US) 2014-07-03 US disclosed
US-20140186335-A1 Certain Compounds, Compositions and Methods EISAI INC. (US) 2014-07-03 US disclosed
US-8268800-B2 Certain compounds, compositions and methods EISAI INC. (US) 2012-09-18 US disclosed
EP-2447272-A1 2'-Fluoro-2'-deoxytetrahydrouridines as cytidine deaminase inhibitors Eisai Inc. (US) 2012-05-02 EP disclosed
US-20090137521-A1 Certain Compounds, Compositions and Methods TAIHO PHARMACEUTICAL CO., LTD. (JP) 2009-05-28 US disclosed
WO-2009052287-A1 2 ' -FLU0R0-2 ' -DEOXYTETRAHYDROURIDINES AS CYTIDINE DEAMINASE INHIBITORS EISAL CORPORATION OF NORTH AMERICA (US) 2009-04-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140186335-A1 Certain Compounds, Compositions and Methods DUT, TYMP, DPYD CDA 134/4885MAPT 1627/4885
US-20150210730-A1 CERTAIN COMPOUNDS, COMPOSITIONS AND METHODS DUT, TYMP, DPYD CDA 134/4885MAPT 1627/4885
US-20090137521-A1 Certain Compounds, Compositions and Methods DUT, TYMP, DPYD CDA 134/4885MAPT 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.