Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOTCH1 | P46531 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30796672 | 0.89 | USP30 (0.51) | USP30RORCPDE4BTACR1KDM4E | |
| SCHEMBL527777 | 0.88 | RORC (0.47) | USP30RORCPDE4BTACR1NOTCH1 | |
| SCHEMBL10277788 | 0.87 | PDE4B (0.57) | USP30RORCPDE4BTACR1 | |
| SCHEMBL10277792 | 0.87 | PDE4B (0.57) | USP30RORCPDE4BTACR1 | |
| SCHEMBL10277789 | 0.87 | PDE4B (0.57) | USP30RORCPDE4BTACR1 | |
| SCHEMBL19385185 | 0.86 | RORC (0.49) | USP30RORCPDE4BKDM4ENOTCH1 | |
| SCHEMBL31171279 | 0.85 | RORC (0.45) | USP30RORCPDE4BTACR1NOTCH1 | |
| SCHEMBL326647 | 0.85 | PDE4B (0.68) | USP30RORCPDE4BTACR1PDE4A | |
| SCHEMBL10277512 | 0.85 | PDE4B (0.68) | USP30RORCPDE4BTACR1PDE4A | |
| SCHEMBL31171278 | 0.85 | RORC (0.45) | USP30RORCPDE4BTACR1NOTCH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006202-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |