Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14892447 | 0.89 | NPBWR1 (0.51) | MAPTNPBWR1ALDH1A1CHEK2SMN1; SMN2 | |
| SCHEMBL1552598 | 0.89 | MAPT (0.54) | MAPTRECQLNPBWR1ALDH1A1LMNA | |
| SCHEMBL12287148 | 0.89 | NPBWR1 (0.48) | MAPTRECQLNPBWR1ALDH1A1LMNA | |
| SCHEMBL14669420 | 0.88 | MAPT (0.53) | MAPTRECQLNPBWR1ALDH1A1LMNA | |
| SCHEMBL2570432 | 0.87 | NPBWR1 (0.47) | MAPTRECQLNPBWR1ALDH1A1LMNA | |
| SCHEMBL12288111 | 0.86 | NPBWR1 (0.46) | MAPTRECQLNPBWR1ALDH1A1LMNA | |
| SCHEMBL14892358 | 0.85 | MAPT (0.50) | MAPTRECQLNPBWR1ALDH1A1LMNA | |
| SCHEMBL14893027 | 0.85 | NPBWR1 (0.46) | MAPTRECQLNPBWR1ALDH1A1LMNA | |
| SCHEMBL2576407 | 0.85 | NPBWR1 (0.47) | MAPTRECQLNPBWR1ALDH1A1LMNA | |
| SCHEMBL12286935 | 0.85 | MAPT (0.53) | MAPTNPBWR1ALDH1A1LMNACHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097238-B2 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE (AU) | 2012-01-17 | — | — | US | disclosed |
| US-8097238-B2 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE (AU) | 2012-01-17 | — | — | US | disclosed |
| US-20070140970-A1 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE | 2007-06-21 | — | — | US | disclosed |
| US-20070140970-A1 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070140970-A1 | Cell targeting conjugates | CD47, CD74, CD2 | MAPT 2452/4885RECQL 3780/4885NPBWR1 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.