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NPBWR1

Neuropeptides B/W receptor type 1 · P48145 · NPBWR1 on Sugi Atlas →

34,235 patent compounds predicted against NPBWR1, 17,509 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL987496 SCHEMBL987496 0.61 13/20
SCHEMBL465462 SCHEMBL465462 0.61 12/20
SCHEMBL987534 SCHEMBL987534 0.61 11/20
SCHEMBL529750 SCHEMBL529750 0.74 10/20
SCHEMBL900794 SCHEMBL900794 0.74 10/20
SCHEMBL677586 SCHEMBL677586 0.56 10/20
SCHEMBL899088 SCHEMBL899088 0.56 10/20
SCHEMBL598575 SCHEMBL598575 0.55 10/20
SCHEMBL370907 SCHEMBL370907 0.50 10/20
SCHEMBL986061 SCHEMBL986061 0.48 10/20
SCHEMBL14711 SCHEMBL14711 0.56 9/20
SCHEMBL347973 SCHEMBL347973 0.54 9/20
SCHEMBL704211 SCHEMBL704211 0.51 9/20
SCHEMBL984018 SCHEMBL984018 0.50 9/20
SCHEMBL986445 SCHEMBL986445 0.63 8/20
SCHEMBL904621 SCHEMBL904621 0.54 8/20
SCHEMBL984971 SCHEMBL984971 0.53 8/20
SCHEMBL986056 SCHEMBL986056 0.50 8/20
SCHEMBL759896 SCHEMBL759896 0.39 8/20
SCHEMBL259520 SCHEMBL259520 0.63 7/20

Clinical trials — most relevant to NPBWR1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell. PHASE4UNKNOWN
Effects of Genotype on Resting State Connectivity During Methamphetamine Administration PHASE4COMPLETED
Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep PHASE3COMPLETED
Efficacy and Safety of an Oral Growth Hormone Drug in the Treatment of Fibromyalgia PHASE2COMPLETED
Bradykinin Receptors and Pain PHASE2COMPLETED
Effects of Exenatide on Hypothalamic Obesity PHASE1/PHASE2COMPLETED
Studying the Influence of LEAP2 on Integrated Endocrine Control of Eating During Semaglutide Treatment PHASE1/PHASE2RECRUITING
Acylated Ghrelin Response to Acute Exercise in Obesity nanCOMPLETED
Relationship of Brain Natriuretic Peptide (BNP) Levels to Cardiac Diagnosis, Operation Performed, Post-operative Course and Outcome nanCOMPLETED
Cue-based Tactile Stimulation and Infant Stress Reactivity nanCOMPLETED
Auricular Vagus Stimulation in Obesity nanACTIVE_NOT_RECRUITING
Brain-Derived Neurotrophic Factor in Obesity and Brain Function nanCOMPLETED
Eating Behavior in Children nanCOMPLETED
Affective Touch, Hedonia and Suicidal Behavior nanCOMPLETED
Insulin Detemir in Obesity Management nanACTIVE_NOT_RECRUITING
The Effect of GLP-1 Receptor Activation on Central Reward and Satiety in Obesity and Diabetes nanCOMPLETED
A Study on the Effects of Combined FMT on Gut Microbiota and Eating Disorder Symptoms in AN nanNOT_YET_RECRUITING
Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly nanRECRUITING
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
Adipogenic Capacity as a Mediator of Weight Gain nanUNKNOWN
Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings nanUNKNOWN
Precision Obesity Medicine: Genetic Prediction of Response to GLP-1/GIP Agonists. nanRECRUITING
Neurogenic Mechanisms in Burning Mouth Syndrome nanCOMPLETED
Gastrointestinal Hormonal Regulation of Obesity nanCOMPLETED
Dopamine Receptor Imaging in Mood Disorders nanCOMPLETED
Biomarkers in Blood and Tissue Samples From Patients With Newly Diagnosed Neuroblastoma nanCOMPLETED
Calorie Restriction in Multiple Sclerosis nanACTIVE_NOT_RECRUITING
Pre- and Post-prandial Levels of Appetite Regulatory Hormones in Adults nanCOMPLETED
Gene x Behavior Interaction in the Look AHEAD Study nanCOMPLETED
Defining the Brain Phenotype of Children With Williams Syndrome nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a NPBWR1 binder may also engage these)

ProteinNameSimilarity
Q56UD9 — 1.000 Q56UD9 →
P49681 — 1.000 P49681 →
Q8MJV3 — 0.992 Q8MJV3 →
P48146 — 0.988 P48146 →
Q8MJV2 — 0.982 Q8MJV2 →
P49660 — 0.981 P49660 →
P30937 — 0.975 P30937 →
SSTR4 Somatostatin receptor type 4 0.972 landscape →
P30935 — 0.962 P30935 →
P30936 — 0.961 P30936 →
SSTR5 Somatostatin receptor type 5 0.960 landscape →
Q9BDQ5 — 0.960 Q9BDQ5 →
SSTR3 Somatostatin receptor type 3 0.959 landscape →
A0T2N3 — 0.959 A0T2N3 →
O97661 — 0.958 O97661 →
O08726 — 0.957 O08726 →
GALR3 Galanin receptor type 3 0.957 landscape →
Q49LX5 — 0.957 Q49LX5 →
HCRTR1 Orexin/Hypocretin receptor type 1 0.956 landscape →
SSTR1 Somatostatin receptor type 1 0.955 landscape →
P2RY6 P2Y purinoceptor 6 0.955 landscape →
NPFFR1 Neuropeptide FF receptor 1 0.955 landscape →
P56718 — 0.954 P56718 →
Q63371 — 0.954 Q63371 →
Q8HYC3 — 0.954 Q8HYC3 →
Q9ERK9 — 0.954 Q9ERK9 →
Q0GBZ5 — 0.954 Q0GBZ5 →
GALR2 Galanin receptor type 2 0.954 landscape →
P58307 — 0.953 P58307 →
O88854 — 0.953 O88854 →