SCHEMBL1007028

SCHEMBL1007028

CC(C)CN=C=Nc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.40
TRPA1 O75762 1/20 0.37
HTR2A P28223 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11746136 0.83 TAAR1 (0.42) MIFTRPA1
SCHEMBL1009278 0.77 MIF (0.44) MIFTRPA1ALDH1A1NOS3NOS1
SCHEMBL2045539 0.76 MIF (0.48) MIFTRPA1ALDH1A1NOS3NOS1
SCHEMBL11748772 0.74 TAAR1 (0.38) MIFTRPA1
SCHEMBL2766190 0.73 MIF (0.41) MIFTRPA1ALDH1A1NOS3NOS1
SCHEMBL16385745 0.73 ALDH1A1 (0.40) MIFALDH1A1
SCHEMBL1007787 0.72 MIF (0.44) MIFALDH1A1NOS3NOS1
SCHEMBL15720506 0.72 MIF (0.44) MIFTRPA1ALDH1A1NOS3NOS1
SCHEMBL27972061 0.72 MIF (0.44) MIFTRPA1HTR2AALDH1A1NOS3
SCHEMBL156948 0.72 MIF (0.60) MIFTRPA1ALDH1A1NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114174427-A Flame-retardant polybutylene terephthalate resin composition 宝理塑料株式会社 2022-03-11 CN disclosed
EP-3941962-A1 A METHOD FOR THE COMBINED PROCESSING OF AT LEAST TWO POLYMER MELTS BASF SE (DE) 2022-01-26 EP disclosed
EP-3713988-A1 METHOD FOR PURIFYING AN ALIPHATIC POLYESTER BASF SE (DE) 2020-09-30 EP disclosed
WO-2020187596-A1 A method for the combined processing of at least two polymer melts BASF SE (DE) 2020-09-24 WO disclosed
CN-107473991-B Method for synthesizing isourea catalyzed by rare earth compound 苏州大学 2020-04-10 CN disclosed
CN-107400354-A A kind of automobile radiators water-supplying chamber 宁波市鄞州红岩汽配厂 2017-11-28 CN disclosed
EP-3114170-A1 EPOXY COMPOSITIONS FRX Polymers, Inc. (US) 2017-01-11 EP disclosed
WO-2015134600-A1 EPOXY COMPOSITIONS FRX POLYMERS, INC. (US) 2015-09-11 WO disclosed
EP-2488585-A1 METHOD FOR CONTINUOUSLY PRODUCING POLYESTER MIXTURES BASF SE (DE) 2012-08-22 EP disclosed
WO-2011045293-A1 METHOD FOR CONTINUOUSLY PRODUCING POLYESTER MIXTURES BASF SE (DE) 2011-04-21 WO disclosed
CN-101955579-A Polymer composition and production method thereof TORAY FIBER RES INST CN CO LTD 2011-01-26 CN disclosed
EP-2268704-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2011-01-05 EP disclosed
EP-2268702-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2011-01-05 EP disclosed
CN-101759969-A Polylactic acid composition and molding product thereof TORAY FIBER RES INST CN CO LTD 2010-06-30 CN disclosed
CN-101759961-A Hydrolysis-resistance polyester composition and preparation method there TORAY FIBER RES INST CN CO LTD 2010-06-30 CN disclosed
WO-2010012695-A1 INCREASING THE HYDROLYSIS RESISTANCE OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2010-02-04 WO disclosed
WO-2009127555-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2009-10-22 WO disclosed
WO-2009127556-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2009-10-22 WO disclosed
CN-100396720-C Aliphatic polyester resin composition, method for production thereof, molded article and foamed article comprising the resin composition UNITIKA LTD (JP) 2008-06-25 CN disclosed
CN-1805999-A Aliphatic polyester resin composition, method for production thereof, molded article and foamed article comprising the resin composition UNITIKA LTD (JP) 2006-07-19 CN disclosed