Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523559 | 0.85 | MAOB (0.56) | MAOBCYP19A1CYP3A4ALDH1A1METAP1 | |
| SCHEMBL25732092 | 0.78 | CYP19A1 (0.61) | CYP19A1ALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL570789 | 0.78 | ALDH1A1 (0.55) | MAOBCYP19A1CYP3A4ALDH1A1HPGD | |
| SCHEMBL10815794 | 0.75 | CYP19A1 (0.66) | MAOBCYP19A1ALDH1A1HPGDKDM4E | |
| SCHEMBL25732148 | 0.74 | ABCB1 (0.56) | MAOBCYP19A1CYP3A4ALDH1A1HPGD | |
| SCHEMBL31619577 | 0.73 | ALDH1A1 (0.55) | MAOBCYP19A1CYP3A4ALDH1A1METAP1 | |
| SCHEMBL1699503 | 0.73 | ALDH1A1 (0.55) | MAOBCYP19A1CYP3A4ALDH1A1METAP1 | |
| SCHEMBL10070190 | 0.73 | ALDH1A1 (0.65) | MAOBCYP19A1CYP3A4ALDH1A1HPGD | |
| SCHEMBL10695151 | 0.72 | CYP19A1 (0.61) | MAOBCYP19A1ALDH1A1HPGDKDM4E | |
| SCHEMBL29194896 | 0.72 | METAP1 (0.50) | MAOBCYP19A1CYP3A4ALDH1A1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012016619-A1 | PHENETHYL, PHENETHYLENE, PHENETHYNE AND INDANONE DERIVATES IN COSMETIC FORMULATIONS, ESPECIALLY FOR USE IN SKIN AGEING PROCESSES | MERCK PATENT GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |