Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15101329 | 0.88 | ENPP2 (0.39) | CNR2TP53KCNH2CYP2C9SMN1; SMN2 | |
| SCHEMBL10070946 | 0.88 | TP53 (0.40) | CNR2TP53FAAHKCNH2CYP2C9 | |
| SCHEMBL10070927 | 0.86 | TP53 (0.39) | CNR2TP53FAAHKCNH2CYP2C9 | |
| SCHEMBL10070430 | 0.85 | TP53 (0.39) | CNR2TP53FAAHKCNH2CYP2C9 | |
| SCHEMBL12894201 | 0.81 | CNR2 (0.35) | CNR2TP53LMNAKMT2A | |
| SCHEMBL10071005 | 0.81 | ENPP2 (0.36) | CNR2TP53KCNH2CYP2C9LMNA | |
| SCHEMBL10070415 | 0.80 | CNR2 (0.40) | CNR2TP53CYP2C9POLBHPGD | |
| SCHEMBL10070434 | 0.80 | CNR2 (0.42) | CNR2TP53FAAHPDE10ARXFP1 | |
| SCHEMBL367841 | 0.79 | TP53 (0.39) | TP53SMN1; SMN2LMNAKMT2A | |
| SCHEMBL10070053 | 0.79 | SMN1; SMN2 (0.42) | CNR2TP53CYP2C9SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |