Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15298547 | 0.95 | ATM (0.59) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL10071701 | 0.95 | ATM (0.59) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL15298546 | 0.95 | ATM (0.59) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL15298544 | 0.95 | ATM (0.59) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL9957170 | 0.95 | ATM (0.59) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL15298555 | 0.93 | ATM (0.57) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL15298548 | 0.93 | ATM (0.57) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL15298545 | 0.93 | ATM (0.57) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL24492922 | 0.92 | ATM (0.53) | ATMCYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL10070681 | 0.90 | ATM (0.61) | ATMCYP19A1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2012088192-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |