Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15298544 | 1.00 | ATM (0.59) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15298547 | 1.00 | ATM (0.59) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15298546 | 1.00 | ATM (0.59) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10071701 | 1.00 | ATM (0.59) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15298545 | 0.98 | ATM (0.57) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15298555 | 0.95 | ATM (0.57) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10071112 | 0.95 | ATM (0.57) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15298548 | 0.95 | ATM (0.57) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10070681 | 0.95 | ATM (0.61) | ATMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15298543 | 0.95 | MEN1 (0.49) | ATMMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655339-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E.I. Du Pont De Nemours And Company (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2012088192-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088192-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |