⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031404 | 0.84 | — | — | |
| SCHEMBL3653566 | 0.83 | KCNA3 (0.33) | — | |
| SCHEMBL2458787 | 0.83 | — | — | |
| SCHEMBL6238419 | 0.81 | JAK2 (0.33) | — | |
| SCHEMBL4629349 | 0.81 | KCNA3 (0.37) | — | |
| SCHEMBL1923112 | 0.77 | — | — | |
| SCHEMBL526347 | 0.77 | — | — | |
| SCHEMBL9031950 | 0.77 | — | — | |
| SCHEMBL49802 | 0.77 | — | — | |
| SCHEMBL5253475 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234546-A | GPX4 inhibitors, pharmaceutical compositions thereof and their use in the treatment of GPX4 mediated diseases | 嘉兴优博生物技术有限公司 | 2023-06-06 | — | — | CN | claimed |
| WO-2021183702-A1 | GPX4 INHIBITORS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING GPX4-MEDIATED DISEASES | EUBULUS BIOTHERAPEUTICS INC. (CN) | 2021-09-16 | — | — | WO | claimed |
| US-20180118718-A1 | Substituted Quinoxaline Derivatives | SELVITA S.A. (PL) | 2018-05-03 | — | — | US | claimed |
| US-7361687-B2 | Arylsulphonamide derivatives and methods of preparing | LABORATOIRES FOURNIER SA (FR) | 2008-04-22 | — | — | US | claimed |
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | LABORATOIRES FOURNIER SA (FR) | 2006-04-20 | — | — | US | claimed |
| US-5300521-A | Fungicides for the control of phytopathogens | SANDOZ LTD. (CH) | 1994-04-05 | — | — | US | claimed |
| EP-0571326-A1 | Pyrazoles | SANDOZ LTD. (CH) | 1993-11-24 | — | — | EP | claimed |
| EP-0207690-B1 | N-SUBSTITUTED GLUTAMIC ACID DERIVATIVE AND PROCESS FOR PRODUCTION AND USE THEREOF | SUNTORY LIMITED (JP) | 1989-12-20 | — | — | EP | claimed |
| US-4701210-A | HERBICIDES | SUNTORY LIMITED (JP) | 1987-10-20 | — | — | US | claimed |
| EP-0207690-A1 | N-Substituted glutamic acid derivative and process for production and use thereof | SUNTORY LIMITED (JP) | 1987-01-07 | — | — | EP | claimed |
| US-4391804-A | Imidazole derivatives and fungicidal composition containing the same | HOKKO CHEMICAL INDUSTRY COMPANY, LTD. (JP) | 1983-07-05 | — | — | US | claimed |
| US-11827626-B2 | Quinolines that modulate SERCA and their use for treating disease | NEURODON CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| CN-116234546-A | GPX4 inhibitors, pharmaceutical compositions thereof and their use in the treatment of GPX4 mediated diseases | 嘉兴优博生物技术有限公司 | 2023-06-06 | — | — | CN | disclosed |
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO PTE. LTD. (SG) | 2023-02-16 | — | — | US | disclosed |
| EP-4116303-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS BTK INHIBITORS FOR THE TREATMENT OF CANCER | Loxo Oncology, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| US-4361563-A | CARDIOTONIC, ANTITHROMBOTIC | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-11-30 | — | — | US | disclosed |
| EP-0008391-A1 | Benzimidazoles, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1980-03-05 | — | — | EP | disclosed |
| US-4159328-A | INSECTICIDES, MITICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1979-06-26 | — | — | US | disclosed |
| US-4059432-A | A 2-SULFONYLOXYETHYL-PHOSPHONIC OR -THIONOPHOSPHONIC ACID DERIVATIVE | MITSUBISHI PETROCHEMICAL CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4059431-A | A 2-SULFONYLOXYETHYL-PHOSPHONIC OR -THIONOPHOSPHONIC ACID DERIVATIVE | MITSUBISHI PETROCHEMICAL CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |