Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451127 | 0.89 | KCNA3 (0.52) | MAPTKCNA3ALDH1A1TAAR1RECQL | |
| SCHEMBL314763 | 0.89 | TSHR (0.40) | SMN1; SMN2 | |
| SCHEMBL3140129 | 0.87 | NPC1 (0.33) | MAPTSMN1; SMN2 | |
| SCHEMBL8583545 | 0.87 | — | — | |
| SCHEMBL126227 | 0.87 | ALDH1A1 (0.34) | LMNAGAAMAPTALDH1A1HPGD | |
| SCHEMBL188983 | 0.87 | KDM4E (0.48) | ALDH1A1HPGDSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL2458787 | 0.87 | — | — | |
| SCHEMBL348920 | 0.87 | ALDH1A1 (0.48) | GAAALDH1A1HTTSMN1; SMN2RECQL | |
| SCHEMBL6721192 | 0.87 | — | — | |
| SCHEMBL2008537 | 0.87 | KCNH2 (0.32) | ALDH1A1KDM4ETAAR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670388-A2 | METHOD OF MAKING OPHTHALMIC DEVICES AND COMPONENTS THEREOF FROM HYDROPHOBIC ACRYLIC (HA) POLYMERS WITH REDUCED OR ELIMINATED GLISTENINGS | Key Medical Technologies, Inc. (US) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012106118-A2 | METHOD OF MAKING OPHTHALMIC DEVICES AND COMPONENTS THEREOF FROM HYDROPHOBIC ACRYLIC (HA) POLYMERS WITH REDUCED OR ELIMINATED GLISTENINGS | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2012-08-09 | — | — | WO | disclosed |
| EP-1543356-A1 | METHOD OF MANUFACTURING OPHTHALMIC LENSES MADE FROM HYDROPHOBIC ACRYLIC POLYMERS | Medennium, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004029675-A1 | METHOD OF MANUFACTURING OPHTHALMIC LENSES MADE FROM HYDROPHOBIC ACRYLIC POLYMERS | MEDENNIUM, INC. (US) | 2004-04-08 | — | — | WO | disclosed |