Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | OGG1 | O15527 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725991 | 0.77 | C1S (0.46) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL2796488 | 0.77 | PARP1 (0.50) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL2796483 | 0.77 | PARP1 (0.50) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL21202944 | 0.71 | C1S (0.41) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL19072138 | 0.71 | NPC1 (0.47) | ALDH1A1GAAMAPTPARP1L3MBTL1 | |
| SCHEMBL13356014 | 0.71 | ALDH1A1 (0.38) | ALDH1A1GAAMAPTLMNANPC1 | |
| SCHEMBL8282535 | 0.70 | C1S (0.50) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL5735430 | 0.70 | C1S (0.50) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL5735423 | 0.70 | C1S (0.50) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL2090387 | 0.70 | C1S (0.50) | ALDH1A1KDM4EPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088192-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |