SCHEMBL10071847

SCHEMBL10071847

CC1(C)CC2(CC(C)(C)c3cc4c(cc32)Oc2ccc(N)cc2O4)c2cc3c(cc21)Oc1cc(N)ccc1O3

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
RAB9A P51151 1/20 0.37
MAPT P10636 4/20 0.36
KDM4E B2RXH2 3/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MITF O75030 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FTO Q9C0B1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21166243 0.83 AHR (0.38) SMN1; SMN2NPC1LMNARAB9A
SCHEMBL21440506 0.83
SCHEMBL31534581 0.77 KDM4E (0.36) SMN1; SMN2NPC1LMNARAB9AMAPT
SCHEMBL9326911 0.77 BACE1 (0.33) SMN1; SMN2NPC1LMNARAB9AMAPT
SCHEMBL806947 0.77 KDM4E (0.36) SMN1; SMN2NPC1LMNARAB9AMAPT
SCHEMBL29549031 0.77 BACE1 (0.33) SMN1; SMN2NPC1LMNARAB9AMAPT
SCHEMBL19398980 0.75 FTO (0.39) FTO
SCHEMBL15695598 0.74 MAPT (0.50) SMN1; SMN2NPC1LMNARAB9AMAPT
SCHEMBL2387123 0.74 MAPT (0.50) SMN1; SMN2NPC1LMNARAB9AMAPT
SCHEMBL30790668 0.74 MAPT (0.50) SMN1; SMN2NPC1LMNARAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616493-B1 POLYMERISATION METHOD UNIV COURT UNIV OF EDINBURGH (GB) 2020-07-01 EP disclosed
US-9018270-B2 Method for producing polymers comprising multiple repeat units of bicyclic diamines UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2015-04-28 US disclosed
US-9018270-B2 Method for producing polymers comprising multiple repeat units of bicyclic diamines UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2015-04-28 US disclosed
US-20130267616-A1 Polymerisation Method UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2013-10-10 US disclosed
US-20130267616-A1 Polymerisation Method UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2013-10-10 US disclosed
WO-2012035327-A1 POLYMERISATION METHOD UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2012-03-22 WO disclosed