Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202805 | 0.85 | BCHE (0.55) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL7715339 | 0.84 | BCHE (0.60) | BCHEKMT2AMAOATSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL420910 | 0.84 | BCHE (0.54) | BCHEKMT2AMAOATSHRGRIN2D | |
| Water SCHEMBL6489575 | 0.83 | BCHE (0.58) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL12394541 | 0.82 | BCHE (0.55) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL12394540 | 0.82 | BCHE (0.55) | BCHEKMT2AMAOATSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL6478440 | 0.82 | BCHE (0.57) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL8200714 | 0.81 | KMT2A (0.58) | BCHEKMT2AMAOATSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL422740 | 0.80 | KMT2A (0.57) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL14266747 | 0.80 | BCHE (0.50) | BCHEKMT2AMAOATSHRGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022260-A1 | PROCESS FOR THE PREPARATION OF PYRIDO [2,1-a] ISOQUINOLINE DERIVATIVES COMPRISING OPTICAL RESOLUTION OF AN ENAMINE | ABRECHT STEFAN (CH) | 2012-01-26 | — | — | US | disclosed |
| US-20120010413-A1 | Process for the Preparation of Pyrido [2,1-a] Isoquinoline Derivatives by Catalytic Asymmetric Hydrogenation of an Enamine | ABRECHT STEFAN (CH) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022260-A1 | PROCESS FOR THE PREPARATION OF PYRIDO [2,1-a] ISOQUINOLINE DERIVATIVES COMPRISING OPTICAL RESOLUTION OF AN ENAMINE | PNPO, ENO1, CHRM1 | BCHE 1011/4885KMT2A 2002/4885MAOA 317/4885 |
| US-20120010413-A1 | Process for the Preparation of Pyrido [2,1-a] Isoquinoline Derivatives by Catalytic Asymmetric Hydrogenation of an Enamine | IDO2, IDO1, H1-2 | BCHE 1450/4885KMT2A 819/4885MAOA 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.