Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ARF6 | P62330 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13300342 | 0.89 | POLB (0.47) | GLAPOLBTRPA1KDM4EMAPT | |
| SCHEMBL1008271 | 0.81 | POLB (0.38) | SMN1; SMN2PTGS1PTGS2POLBPDE4A | |
| SCHEMBL1006043 | 0.79 | POLB (0.49) | SMN1; SMN2PTGS1PTGS2GLAPOLB | |
| SCHEMBL12627781 | 0.77 | CTNNB1 (0.40) | SMN1; SMN2POLBKDM4EMAPTALDH1A1 | |
| SCHEMBL13300341 | 0.75 | POLB (0.50) | GLAPOLBKDM4EMAPTLMNA | |
| SCHEMBL1007170 | 0.74 | KDM4E (0.50) | PTGS2GLAPOLBKDM4EMAPT | |
| SCHEMBL12627773 | 0.73 | ACHE (0.39) | KDM4EMAPT | |
| SCHEMBL13300344 | 0.72 | NPC1 (0.42) | SMN1; SMN2GLAPOLBKDM4EMAPT | |
| SCHEMBL12627774 | 0.71 | MAPT (0.41) | SMN1; SMN2MAPT | |
| SCHEMBL15528052 | 0.69 | NPC1 (0.36) | SMN1; SMN2GLATRPA1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125789-B1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-03-16 | — | — | EP | disclosed |
| EP-2275422-A1 | Pyrimidinylpyrazoles as insecticide and parasiticide agents | Bayer CropScience AG (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-2125789-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | Bayer CropScience AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077483-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | PIR, ITPA, DDT | SMN1; SMN2 2602/4885PTGS1 1970/4885PTGS2 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.