Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688497 | 1.00 | GAA (0.53) | GAAMEN1KMT2APTGS2PTGS1 | |
| SCHEMBL13310038 | 0.82 | GAA (0.49) | GAAMEN1KMT2APTGS2PTGS1 | |
| SCHEMBL688859 | 0.82 | GAA (0.49) | GAAMEN1KMT2APTGS2PTGS1 | |
| SCHEMBL688340 | 0.78 | PTGS2 (0.52) | GAAKMT2APTGS2PTGS1L3MBTL1 | |
| SCHEMBL10073338 | 0.78 | PTGS2 (0.52) | GAAKMT2APTGS2PTGS1L3MBTL1 | |
| SCHEMBL699369 | 0.78 | MEN1 (0.41) | MEN1KMT2APTGS2PTGS1L3MBTL1 | |
| SCHEMBL687767 | 0.74 | PTGS1 (0.47) | MEN1KMT2APTGS2PTGS1 | |
| SCHEMBL6461535 | 0.74 | MEN1 (0.47) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL689132 | 0.73 | PTGS2 (0.51) | PTGS2PTGS1L3MBTL1 | |
| SCHEMBL687929 | 0.72 | PTGS2 (0.54) | PTGS2PTGS1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-B1 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2012-02-29 | — | — | EP | disclosed |
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |