Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688894 | 1.00 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL687786 | 0.80 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL688328 | 0.80 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL687788 | 0.80 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL688329 | 0.80 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL688973 | 0.79 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL688975 | 0.79 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL688974 | 0.79 | ALDH1A1 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL688439 | 0.79 | MEN1 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10072758 | 0.79 | MEN1 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-B1 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2012-02-29 | — | — | EP | disclosed |
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |