Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10047737 | 0.96 | MEN1 (0.40) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL5738466 | 0.90 | KMT2A (0.38) | KMT2AMEN1NPSR1POLBCYP2C9 | |
| SCHEMBL10072989 | 0.84 | KMT2A (0.45) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL10047750 | 0.81 | KMT2A (0.43) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL10072991 | 0.74 | KMT2A (0.55) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL10047735 | 0.71 | KMT2A (0.51) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL19938125 | 0.71 | KMT2A (0.39) | KMT2AMEN1ALDH1A1NPSR1HTT | |
| SCHEMBL5739253 | 0.71 | KMT2A (0.39) | KMT2AMEN1ALDH1A1NPSR1HTT | |
| SCHEMBL38658428 | 0.71 | KMT2A (0.39) | KMT2AMEN1ALDH1A1NPSR1HTT | |
| SCHEMBL19924259 | 0.71 | KMT2A (0.39) | KMT2AMEN1ALDH1A1NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083599-A1 | Biomolecular Labelling Using Multifunctional Biotin Analogues | UNIVERSITY OF NOTTINGHAM (GB) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083599-A1 | Biomolecular Labelling Using Multifunctional Biotin Analogues | BTD, URB2, RAET1L | KMT2A 2622/4885MEN1 3602/4885PTGS1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.