SCHEMBL10073153

SCHEMBL10073153

O=C1NC(CO)c2nc(co2)-c2nc(co2)-c2nc(co2)-c2nc(c(O)o2)-c2nc(co2)-c2nc(co2)-c2nc1co2

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TERT O14746 6/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075154 0.83 TERT (0.44) TERT
SCHEMBL10073151 0.77 TERT (0.55) TERT
SCHEMBL801051 0.69 TERT (0.37) TERT
SCHEMBL13587899 0.69 TERT (0.45) TERT
SCHEMBL800775 0.68 TERT (0.44) TERT
SCHEMBL13878331 0.65 TERT (0.58) TERT
SCHEMBL10045828 0.63 TERT (0.60) TERT
SCHEMBL13878329 0.63 TERT (0.44) TERT
SCHEMBL800934 0.60 TERT (0.44) TERT
SCHEMBL12299175 0.59 TERT (0.44) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093235-B2 Macrocyclic compounds which stabilize G-Quadruplex DNA and RNA RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-01-10 US disclosed