⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24080870 | 1.00 | — | — | |
| SCHEMBL18654175 | 1.00 | — | — | |
| SCHEMBL13573716 | 1.00 | — | — | |
| SCHEMBL24936416 | 0.80 | — | — | |
| SCHEMBL12337502 | 0.78 | — | — | |
| SCHEMBL12430384 | 0.78 | — | — | |
| SCHEMBL12829711 | 0.76 | — | — | |
| SCHEMBL13184612 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL14477350 | 0.76 | — | — | |
| SCHEMBL12964263 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225610-B1 | PROCESS FOR THE PREPARATION OF POLYMERS BY COUPLING REACTIONS | SUMITOMO CHEMICAL CO (JP) | 2021-09-29 | — | — | EP | disclosed |
| EP-2431036-B1 | Macrocyclic lactone compounds and methods for their use | ELIXIR MEDICAL CORP (US) | 2017-04-12 | — | — | EP | disclosed |
| US-9579328-B2 | Prostaglandin and vasoconstrictor pharmaceutical compositions and methods of use | ALLERGAN, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2982679-A1 | IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE | Idera Pharmaceuticals, Inc. (US) | 2016-02-10 | — | — | EP | disclosed |
| EP-2702993-A1 | Macrocyclic lactone compounds and methods for their use | Elixir Medical Corporation (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2431036-A1 | Macrocyclic lactone compounds and methods for their use | Elixir Medical Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2008106640-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | CEDARS-SINAI MEDICAL CENTER (US) | 2008-09-04 | — | — | WO | disclosed |