Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81831 | 0.97 | TDP1 (0.70) | TDP1SIGMAR1MAOAMAOBADRA1A | |
| Ammonia Solution, Strong SCHEMBL27512246 | 0.95 | TDP1 (0.67) | TDP1SIGMAR1MAOAMAOBADRA1A | |
| Hydrochloric Acid SCHEMBL28970403 | 0.95 | TDP1 (0.67) | TDP1SIGMAR1MAOAMAOBADRA1A | |
| Phosphine SCHEMBL7322770 | 0.95 | TDP1 (0.67) | TDP1SIGMAR1MAOAMAOBADRA1A | |
| Fluoride Ion SCHEMBL5446842 | 0.92 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBADRA1A | |
| Ethylene SCHEMBL28160202 | 0.92 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBADRA1A | |
| SCHEMBL9460180 | 0.92 | TDP1 (0.64) | TDP1SIGMAR1MAOAMAOBADRA1A | |
| SCHEMBL9092107 | 0.90 | TDP1 (0.61) | TDP1SIGMAR1MAOAMAOBNPC1 | |
| Propane SCHEMBL28091962 | 0.90 | TDP1 (0.61) | TDP1SIGMAR1MAOAMAOBADRA1A | |
| SCHEMBL28792071 | 0.90 | TDP1 (0.67) | TDP1SIGMAR1MAOAMAOBADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804464-B1 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INT INC (US) | 2002-05-08 | — | — | EP | claimed |
| US-6011158-A | PEPTIDE ALDEHYDE COMPOUNDS HAVING ARGININE OR ARGININE MIMICS AT P1 AND PYRIDONE, PYRIMIDONE, OR URACIL GROUPS AS PART OF THE PEPTIDE BACKBONE. THESE COMPOUNDS ARE POTENT INHIBITORS OF THROMBIN IN VIVO AND IN VITRO. | CORVAS INTERNATIONAL, INC. (US) | 2000-01-04 | — | — | US | claimed |
| EP-0804464-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-11-05 | — | — | EP | claimed |
| WO-1996018644-A9 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | — | 1996-08-01 | — | — | WO | claimed |
| WO-1996018644-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1996-06-20 | — | — | WO | claimed |
| CN-116199610-B | Compounds having glycosidase inhibitory activity, salts and hydrates thereof and use thereof | 中国科学院化学研究所 | 2025-03-25 | — | — | CN | disclosed |
| CN-116199610-A | Compounds having glycosidase inhibitory activity, salts and hydrates thereof and use thereof | 中国科学院化学研究所 | 2023-06-02 | — | — | CN | disclosed |
| US-9469657-B2 | Glycosidase inhibitors | MERCK PATENT GMBH (DE) | 2016-10-18 | — | — | US | disclosed |
| US-9272990-B2 | Lysophosphatidic acid receptor antagonists and their use in the treatment fibrosis | AMIRA PHARMACEUTICALS, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| EP-2748171-B1 | PYRANO [3, 2 - D][1, 3]THIAZOLE AS GLYCOSIDASE INHIBITORS | MERCK PATENT GMBH (DE) | 2016-02-03 | — | — | EP | disclosed |
| CN-103347510-B | Lysophosphatidic acid receptor antagonists and their use in the treatment of fibrosis | AMIRA PHARMACEUTICALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| EP-2648714-B1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND USES THEREOF | AMIRA PHARMACEUTICALS INC (US) | 2015-11-18 | — | — | EP | disclosed |
| EP-0512865-A2 | Novel cholesterol lowering compounds | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5102881-A | Leukotriene biosynthesis inhibitor | MERCK FROSST CANADA, INC. (CA) | 1992-04-07 | — | — | US | disclosed |
| WO-1992004045-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |
| EP-0349062-A1 | Quinoline ether alkanoic acid | MERCK FROSST CANADA INC. (CA) | 1990-01-03 | — | — | EP | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |
| US-3931196-A | Phosphinolines and phosphindolines | MONASH UNIVERSITY (AU) | 1976-01-06 | — | — | US | disclosed |