Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688256 | 1.00 | LMNA (0.43) | LMNAALDH1A1PPARGNFE2L2CXCR2 | |
| SCHEMBL31051131 | 0.81 | PPARG (0.47) | LMNAPPARGNFE2L2CXCR2PTPN1 | |
| SCHEMBL688622 | 0.80 | LMNA (0.41) | LMNAALDH1A1PPARGNFE2L2PTGES2 | |
| SCHEMBL13343069 | 0.80 | LMNA (0.41) | LMNAALDH1A1PPARGNFE2L2PTGES2 | |
| SCHEMBL688272 | 0.80 | PPARG (0.46) | LMNAPPARGNFE2L2CXCR2PTPN1 | |
| SCHEMBL687983 | 0.80 | PPARG (0.46) | LMNAPPARGNFE2L2CXCR2PTGES2 | |
| SCHEMBL688271 | 0.80 | PPARG (0.46) | LMNAPPARGNFE2L2CXCR2PTPN1 | |
| SCHEMBL687984 | 0.80 | PPARG (0.46) | LMNAPPARGNFE2L2CXCR2PTGES2 | |
| SCHEMBL687780 | 0.78 | PPARG (0.45) | LMNAPPARGNFE2L2CXCR2PTPN1 | |
| SCHEMBL687781 | 0.78 | PPARG (0.45) | LMNAPPARGNFE2L2CXCR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-B1 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2012-02-29 | — | — | EP | disclosed |
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |