Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479683 | 0.98 | GAA (0.43) | GAAMAPTALDH1A1HPGDPOLB | |
| SCHEMBL10479678 | 0.98 | GAA (0.43) | GAAMAPTALDH1A1HPGDPOLB | |
| SCHEMBL10844131 | 0.95 | GAA (0.41) | GAAMAPTALDH1A1HPGDPOLB | |
| SCHEMBL10844137 | 0.95 | GAA (0.41) | GAAMAPTALDH1A1HPGDPOLB | |
| SCHEMBL20664377 | 0.94 | NAAA (0.42) | GAAMAPTALDH1A1HPGDPOLB | |
| SCHEMBL10479725 | 0.93 | NAAA (0.44) | GAAMAPTHPGDPOLBHTT | |
| SCHEMBL10479724 | 0.93 | NAAA (0.44) | GAAMAPTHPGDPOLBHTT | |
| SCHEMBL28623965 | 0.93 | MAPT (0.49) | GAAMAPTALDH1A1HPGDPOLB | |
| SCHEMBL10480056 | 0.92 | NAAA (0.47) | GAAMAPTHTTPKMMEN1 | |
| SCHEMBL10480059 | 0.92 | NAAA (0.47) | GAAMAPTHTTPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |