Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | DCK | P27707 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24507690 | 0.91 | MAP4K4 (0.56) | MAP4K4DCKGAAPOLBACHE | |
| SCHEMBL26714156 | 0.84 | POLB (0.54) | MAP4K4DCKGAAPOLBACHE | |
| SCHEMBL7586510 | 0.82 | AR (0.52) | MAP4K4DCKGAAPOLBACHE | |
| SCHEMBL7586504 | 0.82 | MAP4K4 (0.49) | MAP4K4DCKGAAPOLBACHE | |
| SCHEMBL9131619 | 0.82 | GAA (0.53) | MAP4K4GAAPOLBRCE1CYP1A2 | |
| SCHEMBL7173106 | 0.81 | MAP4K4 (0.50) | MAP4K4DCKGAAPOLBACHE | |
| SCHEMBL29390597 | 0.81 | MAP4K4 (0.50) | MAP4K4DCKGAAPOLBACHE | |
| SCHEMBL30449029 | 0.81 | MAP4K4 (0.50) | MAP4K4DCKGAAPOLBACHE | |
| SCHEMBL7173109 | 0.81 | MAP4K4 (0.50) | MAP4K4DCKGAAPOLBACHE | |
| SCHEMBL16202033 | 0.81 | MAP4K4 (0.50) | MAP4K4DCKGAAPOLBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076498-B1 | PREPARATION OF AZOXYSTROBIN | SYNGENTA LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| US-8552185-B2 | Preparation of azoxystrobin | SYNGENTA LIMITED (GB) | 2013-10-08 | — | — | US | disclosed |
| EP-1891020-B1 | PROCESSES FOR THE PREPARATION OF AZOXYSTROBIN USING DABCO AS A CATALYST AND NOVEL INTERMEDIATES USED IN THE PROCESSES | SYNGENTA LTD (GB) | 2013-06-05 | — | — | EP | disclosed |
| US-8124761-B2 | Coupling of methyl (E)-2-{2-[6-chloropyrimidin-4-yloxy]phenyl}-3-methoxyacrylate with 2-cyanophenyl in DMF with 2 mol % DABCO; significantly smaller amounts of this relatively expensive catalyst may be used without compromising the yield | SYNGENTA LIMITED (GB) | 2012-02-28 | — | — | US | disclosed |
| US-20100036124-A1 | PREPARATION OF AZOXYSTROBIN | SYNGENTA LIMITED (GB) | 2010-02-11 | — | — | US | disclosed |
| US-20080214587-A1 | Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| WO-2008043978-A1 | PREPARATION OF AZOXYSTROBIN | SYNGENTA LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036124-A1 | PREPARATION OF AZOXYSTROBIN | CYP51A1, CYP1B1, CYP2D6 | MAP4K4 3132/4885DCK 2716/4885GAA 642/4885 |
| US-20080214587-A1 | Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes | DDT, AOC3, DAO | MAP4K4 786/4885DCK 281/4885GAA 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.