Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | DCK | P27707 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24507690 | 0.89 | MAP4K4 (0.56) | MAP4K4POLBGAAGCKSYK | |
| SCHEMBL7586510 | 0.87 | AR (0.52) | MAP4K4POLBGAAGCKDCK | |
| SCHEMBL26714156 | 0.85 | POLB (0.54) | MAP4K4POLBGAADCKALDH1A1 | |
| SCHEMBL7173109 | 0.82 | MAP4K4 (0.50) | MAP4K4POLBGAASYKDCK | |
| SCHEMBL30449029 | 0.82 | MAP4K4 (0.50) | MAP4K4POLBGAASYKDCK | |
| SCHEMBL29390597 | 0.82 | MAP4K4 (0.50) | MAP4K4POLBGAASYKDCK | |
| SCHEMBL10049643 | 0.82 | MAP4K4 (0.50) | MAP4K4POLBGAASYKDCK | |
| SCHEMBL7173106 | 0.82 | MAP4K4 (0.50) | MAP4K4POLBGAASYKDCK | |
| SCHEMBL5081706 | 0.81 | AR (0.53) | MAP4K4POLBGAAGCKDCK | |
| SCHEMBL10073931 | 0.81 | MAP4K4 (0.55) | MAP4K4POLBGAASYKDCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3040073-B1 | APPLICATIONS OF SUBSTITUENT BENZYLOXY GROUP CONTAINING ETHER COMPOUNDS FOR PREPARING ANTITUMOR DRUGS | SINOCHEM CORP (CN) | 2020-07-08 | — | — | EP | disclosed |
| US-9895346-B2 | Applications of substituent benzyloxy group containing ether compounds for preparing antitumor drugs | SINOCHEM CORPORATION (CN) | 2018-02-20 | — | — | US | disclosed |
| US-9895346-B2 | Applications of substituent benzyloxy group containing ether compounds for preparing antitumor drugs | SINOCHEM CORPORATION (CN) | 2018-02-20 | — | — | US | disclosed |
| US-20170296508-A1 | Applications of Substituent Benzyloxy Group Containing Ether Compounds for Preparing Antitumor Drugs | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| US-20170296508-A1 | Applications of Substituent Benzyloxy Group Containing Ether Compounds for Preparing Antitumor Drugs | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| US-9643935-B2 | Process for preparing 4,6-BIS (aryloxy) pyrimidine derivatives | CHEMINOVA A/S (DK) | 2017-05-09 | — | — | US | disclosed |
| US-20160249615-A1 | Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors | BASF SE (DE) | 2016-09-01 | — | — | US | disclosed |
| EP-3040073-A1 | APPLICATIONS OF SUBSTITUENT BENZYLOXY GROUP CONTAINING ETHER COMPOUNDS FOR PREPARING ANTITUMOR DRUGS | Sinochem Corporation (CN) | 2016-07-06 | — | — | EP | disclosed |
| US-20160145219-A1 | STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2016-05-26 | — | — | US | disclosed |
| US-20160145202-A1 | Strobilurin Type Compounds for Combating Phytopathogenic Fungi | BASF SE (DE) | 2016-05-26 | — | — | US | disclosed |
| US-20160137612-A1 | PROCESS FOR PREPARING 4,6-BIS (ARYLOXY) PYRIMIDINE DERIVATIVES | CHEMINOVA A/S (DK) | 2016-05-19 | — | — | US | disclosed |
| US-20160122327-A1 | STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2016-05-05 | — | — | US | disclosed |
| US-9271501-B2 | Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors | BASF SE (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20140323305-A1 | Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors | BASF SE (DE) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122327-A1 | STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | SNX1, DPM1, SNU13 | MAP4K4 4435/4885POLB 4052/4885GAA 244/4885 |
| US-20170296508-A1 | Applications of Substituent Benzyloxy Group Containing Ether Compounds for Preparing Antitumor Drugs | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MCL1, TPD52L2 | MAP4K4 2015/4885POLB 3772/4885GAA 4031/4885 |
| US-20160145219-A1 | STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | DPM1, CROCC, SNX1 | MAP4K4 4422/4885POLB 4251/4885GAA 192/4885 |
| US-20160145202-A1 | Strobilurin Type Compounds for Combating Phytopathogenic Fungi | DPM1, CROCC, SNX1 | MAP4K4 4422/4885POLB 4251/4885GAA 192/4885 |
| US-20140323305-A1 | Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors | SQOR, COX5B, UQCRB | MAP4K4 4770/4885POLB 198/4885GAA 633/4885 |
| US-20160249615-A1 | Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors | SQOR, COX5B, UQCRB | MAP4K4 4770/4885POLB 198/4885GAA 633/4885 |
| US-20160137612-A1 | PROCESS FOR PREPARING 4,6-BIS (ARYLOXY) PYRIMIDINE DERIVATIVES | NUDT1, UMPS, DPYD | MAP4K4 660/4885POLB 16/4885GAA 1697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.