SCHEMBL1007398

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1007660	0.87	GRIA2 (0.57)	GRIA2CYP2C9CYP2C19POLBCYP2D6
	SCHEMBL1006841	0.83	POLB (0.51)	GRIA2CYP2C9CYP2C19POLBCYP2D6
	SCHEMBL1007201	0.83	POLB (0.56)	GRIA2CYP2C19POLBPOLQMAPT
	SCHEMBL1006269	0.83	GRIA2 (0.55)	GRIA2CYP2C9CYP2C19POLBCYP2D6
	SCHEMBL1007152	0.82	POLB (0.54)	GRIA2CYP2C9CYP2C19POLBCYP2D6
	SCHEMBL1009106	0.82	GRIA2 (0.54)	GRIA2CYP2C19POLBPOLQMAPT
	SCHEMBL1007029	0.81	LMNA (0.56)	GRIA2CYP2C9CYP2C19POLBCYP2D6
	SCHEMBL1891273	0.78	SMN1; SMN2 (0.56)	CYP2C19MAPTSMN1; SMN2TSHRGAA
	SCHEMBL3137412	0.78	GRIA2 (0.77)	GRIA2CYP2C9CYP2C19CYP2D6GAA
	SCHEMBL1895722	0.78	MAPT (0.56)	CYP2C19MAPTSMN1; SMN2TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.