Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073986 | 0.83 | GAA (0.45) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16643752 | 0.77 | GAA (0.55) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24404818 | 0.73 | CNR1 (0.51) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL26077723 | 0.71 | GAA (0.55) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL273097 | 0.70 | ATM (0.60) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28509439 | 0.69 | ALDH1A1 (0.55) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28510286 | 0.69 | ALDH1A1 (0.55) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28509438 | 0.69 | ALDH1A1 (0.55) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8568083 | 0.69 | GAA (0.69) | GAAATMNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22987577 | 0.69 | GAA (0.59) | GAAATMNAMPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148538-B2 | N-alkyl-heterocyclyl carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-04-03 | — | — | US | disclosed |