Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Thiamine Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.98 |
| ▸ | TKT | P29401 | 12/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiamine Ion SCHEMBL29572584 | 1.00 | HSP90AA1 (0.98) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL7090274 | 1.00 | HSP90AA1 (0.98) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL29445547 | 1.00 | HSP90AA1 (0.98) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL9618673 | 0.99 | HSP90AA1 (0.95) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL7110640 | 0.99 | HSP90AA1 (0.95) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL9391504 | 0.99 | HSP90AA1 (0.95) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL7200449 | 0.99 | HSP90AA1 (0.95) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL5189557 | 0.99 | HSP90AA1 (0.95) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL10636119 | 0.99 | HSP90AA1 (0.95) | HSP90AA1TKTTDP1KDM4ELMNA | |
| Thiamine Ion SCHEMBL9618672 | 0.99 | HSP90AA1 (0.95) | HSP90AA1TKTTDP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 116922 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144771-A1 | Use of Triheptanoin Oil for Primary-Specific Pyruvate Dehydrogenase Complex (PDC) Deficiency | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2026-05-28 | — | — | US | claimed |
| US-20260144835-A1 | MULTIFUNCTIONAL NUTRACEUTICAL FOR ENHANCING FEMALE HEALTH | Beltran, Robert R. (US) | 2026-05-28 | — | — | US | claimed |
| US-20260144836-A1 | NUTRACEUTICAL FOR ENHANCED COGNITIVE PERFORMANCE | Herbanized Wellness, LLC (US) | 2026-05-28 | — | — | US | claimed |
| EP-4747627-A1 | METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS | Matterworks Inc (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122074633-A | Flavour composition, aqueous food composition containing said flavour composition, preparation and use thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122087604-A | Pear variety classification method and system based on minimum feature component diversity | — | 2026-05-26 | — | — | CN | claimed |
| CN-119702255-B | Technology for recovering apatite by floatation of iron tailings | ANHUI MAGANG LUOHE MINE Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122074613-A | Bergamot effervescent tablet based on microencapsulation inclusion technology and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094368-A | Antimony-based solar cell and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12635714-B2 | Compositions and methods for providing a health benefit to a growing animal | Société des Produits Nestlé S.A. (CH) | 2026-05-26 | — | — | US | claimed |
| US-4042698-A | Treatment of myasthenia gravis and oral medication therefor | ZAPPIA JOSEPH FRANCIS | 1977-08-16 | — | — | US | claimed |
| US-4006219-A | Composition and method for countering effects of alcohol consumption | CERES PHARMACAL COMPANY (US) | 1977-02-01 | — | — | US | claimed |
| US-4000322-A | BLENDING, HONEY | GERBER PRODUCTS COMPANY (US) | 1976-12-28 | — | — | US | claimed |
| US-3997399-A | CANDIDA LIPOLYTIC YEAST | INSTITUT FRANCAIS DU PETROLE, DES CARBURANTS ET LUBRIFIANTS ET ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERES ELF (FR) | 1976-12-14 | — | — | US | claimed |
| US-3993543-A | Process for producing pyruvic acid by fermentation | AJINOMOTO CO., INC. (JA) | 1976-11-23 | — | — | US | claimed |
| US-3992555-A | METABOLIZABLE FAT, VITAMINS, AND IRON COMPOUNDS | VITAMINS, INC. (US) | 1976-11-16 | — | — | US | claimed |
| US-3980523-A | HAEMOPHILIUS GALLINARUM, SODIUM CHLORIDE, REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE | RIMLER RICHARD B | 1976-09-14 | — | — | US | claimed |
| US-3966988-A | Flavoring compositions and processes utilizing dithiazine compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-06-29 | — | — | US | claimed |
| US-3954979-A | THIAMINE, RIBOFLAVIN, NIACIN, DEHYDRATION, PASTEURIZATION | CERES PRODUCTS COMPANY, INC. (US) | 1976-05-04 | — | — | US | claimed |
| US-3946115-A | GRINDING, EXTRUSION | RALSTON PURINA COMPANY (US) | 1976-03-23 | — | — | US | claimed |