Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.66 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.66 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.66 |
| ▸ | LAP3 | P28838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078258 | 1.00 | DPP4 (0.66) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL10078085 | 1.00 | DPP4 (0.66) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL10054407 | 1.00 | DPP4 (0.66) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL10075285 | 0.90 | DPP4 (0.67) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL10054393 | 0.90 | DPP4 (0.67) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL10077064 | 0.90 | DPP4 (0.67) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL10074988 | 0.86 | DPP4 (0.55) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL10074991 | 0.82 | DPP4 (0.50) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL10078091 | 0.82 | DPP4 (0.49) | DPP4DPP7DPP8DPP9LAP3 | |
| SCHEMBL6873316 | 0.80 | DPP4 (0.55) | DPP4DPP7DPP8DPP9LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |