SCHEMBL10077064

SCHEMBL10077064

N[C@H](Cc1ccccc1)[C@@H](O)C(=O)NCCCC[C@H](N)C(=O)N1CCSC1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 13/20 0.67
DPP7 Q9UHL4 7/20 0.67
DPP8 Q6V1X1 4/20 0.67
DPP9 Q86TI2 3/20 0.67
LAP3 P28838 2/20 0.52
ANPEP P15144 1/20 0.52
RNPEP Q9H4A4 1/20 0.52
DNPEP Q9ULA0 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075285 1.00 DPP4 (0.67) DPP4DPP7DPP8DPP9LAP3
SCHEMBL10054393 1.00 DPP4 (0.67) DPP4DPP7DPP8DPP9LAP3
SCHEMBL6873316 0.91 DPP4 (0.55) DPP4DPP7DPP8DPP9LAP3
SCHEMBL10078258 0.90 DPP4 (0.66) DPP4DPP7DPP8DPP9LAP3
SCHEMBL10074147 0.90 DPP4 (0.66) DPP4DPP7DPP8DPP9LAP3
SCHEMBL10078085 0.90 DPP4 (0.66) DPP4DPP7DPP8DPP9LAP3
SCHEMBL10054407 0.90 DPP4 (0.66) DPP4DPP7DPP8DPP9LAP3
SCHEMBL10074713 0.88 DPP4 (0.70) DPP4DPP7DPP8DPP9
SCHEMBL10074136 0.87 DPP4 (0.57) DPP4DPP7DPP8DPP9LAP3
SCHEMBL10074481 0.86 DPP4 (0.55) DPP4DPP7DPP8DPP9LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120028995-A1 NOVEL COMPOUNDS FOR MEDICAL USE AS PEPTIDASE EFFECTORS IMTM GMBH (DE) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120028995-A1 NOVEL COMPOUNDS FOR MEDICAL USE AS PEPTIDASE EFFECTORS SERPINB1, CMA1, CPA3 DPP4 121/4885DPP7 86/4885DPP8 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.