Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | IL6ST | P40189 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 9/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049895 | 0.91 | PPARA (0.40) | PPARAAGTR2IL6STIDH1NAAA | |
| SCHEMBL2676221 | 0.87 | PPARA (0.38) | PPARAAGTR2IL6STIDH1NAAA | |
| SCHEMBL2676265 | 0.87 | PPARA (0.38) | PPARAAGTR2IL6STIDH1NAAA | |
| SCHEMBL2676409 | 0.87 | PPARA (0.38) | PPARAAGTR2IL6STIDH1NAAA | |
| SCHEMBL9947401 | 0.77 | CHRM1 (0.48) | PPARAIDH1 | |
| SCHEMBL29516311 | 0.77 | PPARA (0.43) | PPARAAGTR2IL6STIDH1NAAA | |
| SCHEMBL8555423 | 0.76 | GAA (0.46) | PPARAAGTR2IL6STIDH1NAAA | |
| SCHEMBL1915787 | 0.76 | PPARA (0.42) | PPARAAGTR2IL6STIDH1NAAA | |
| SCHEMBL1915789 | 0.76 | PPARA (0.42) | PPARAAGTR2IL6STIDH1NAAA | |
| SCHEMBL16681720 | 0.76 | PPARA (0.40) | PPARAAGTR2IL6STIDH1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173649-B2 | Glucokinase activator | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20100016304-A1 | GLUCOKINASE ACTIVATOR | TEIJIN LIMITED (JP) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016304-A1 | GLUCOKINASE ACTIVATOR | GCK, GCKR, GALK1 | PPARA 2242/4885AGTR2 856/4885IL6ST 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.