SCHEMBL8555423

SCHEMBL8555423

CCC(C(=O)N1C(=O)OCC1Cc1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
PPARA Q07869 1/20 0.46
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
IDH1 O75874 4/20 0.43
IL6ST P40189 1/20 0.42
NAAA Q02083 1/20 0.41
BCHE P06276 1/20 0.41
AGTR2 P50052 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CHRM1 P11229 1/20 0.40
POLB P06746 1/20 0.40
FAAH O00519 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9258788 0.93 PPARA (0.44) GAAPPARAKDM4EALDH1A1TSHR
SCHEMBL25377195 0.92 PPARA (0.43) GAAPPARAKDM4EALDH1A1TSHR
SCHEMBL8152073 0.92 PPARA (0.43) GAAPPARAKDM4EALDH1A1TSHR
SCHEMBL8555074 0.91 PPARA (0.47) PPARAIDH1IL6STNAAAAGTR2
SCHEMBL29516311 0.89 PPARA (0.43) PPARAIDH1IL6STNAAAAGTR2
SCHEMBL9947401 0.89 CHRM1 (0.48) PPARAIDH1CHRM1
SCHEMBL1915787 0.88 PPARA (0.42) PPARAIDH1IL6STNAAAAGTR2
SCHEMBL1915789 0.88 PPARA (0.42) PPARAIDH1IL6STNAAAAGTR2
SCHEMBL8403671 0.86 CSNK2B (0.49) GAAPPARAKDM4EALDH1A1TSHR
SCHEMBL2206996 0.85 PPARA (0.47) PPARAIDH1IL6STNAAAAGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848957-A1 Fas LIGAND SOLUBILIZATION INHIBITOR KANEBO LTD. (JP) 1998-06-24 EP disclosed