Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15164347 | 0.90 | F2RL1 (0.62) | MAPTNPC1RAB9ASMN1; SMN2F2RL1 | |
| SCHEMBL17230496 | 0.87 | MAPT (0.56) | MAPTNPC1RAB9ASMN1; SMN2F2RL1 | |
| SCHEMBL15164336 | 0.87 | ALOX5 (0.60) | MAPTNPC1RAB9ASMN1; SMN2F2RL1 | |
| SCHEMBL275760 | 0.87 | F2RL1 (0.58) | MAPTNPC1RAB9AF2RL1LMNA | |
| SCHEMBL27590309 | 0.87 | SMN1; SMN2 (0.59) | MAPTNPC1RAB9ASMN1; SMN2F2RL1 | |
| SCHEMBL15603601 | 0.85 | APP (0.50) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28577101 | 0.84 | ALOX5 (0.57) | F2RL1ALDH1A1TDP1ALOX5 | |
| SCHEMBL22693977 | 0.84 | MAPT (0.69) | MAPTNPC1RAB9ASMN1; SMN2F2RL1 | |
| SCHEMBL28579204 | 0.84 | ALOX5 (0.57) | F2RL1LMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL490534 | 0.84 | TDP1 (0.70) | MAPTNPC1RAB9ASMN1; SMN2F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002290-B1 | SYNTHESIS OF DEOXYCHOLIC ACID (DCA) | ALLERGAN SALES LLC (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10175573-B2 | Curable composition and color filter | FUJIFILM CORPORATION (JP) | 2019-01-08 | — | — | US | disclosed |
| EP-3002290-A2 | SYNTHESIS OF DEOXYCHOLIC ACID (DCA) | Kythera Biopharmaceuticals, Inc. (US) | 2016-04-06 | — | — | EP | disclosed |
| US-20150316844-A1 | CURABLE COMPOSITION AND COLOR FILTER | FUJIFILM CORPORATION (JP) | 2015-11-05 | — | — | US | disclosed |
| US-20150316844-A1 | CURABLE COMPOSITION AND COLOR FILTER | FUJIFILM CORPORATION (JP) | 2015-11-05 | — | — | US | disclosed |
| EP-2407475-A2 | Synthetic Bile Acid Composition, Method, and Preparation | Kythera Biopharmaceuticals, Inc. (US) | 2012-01-18 | — | — | EP | disclosed |