SCHEMBL1007445

SCHEMBL1007445

ClC(Cl)(Cl)Oc1[c]cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9528097 0.83
SCHEMBL7460444 0.83
SCHEMBL9030688 0.83
SCHEMBL9528791 0.83
SCHEMBL3095098 0.79 TSHR (0.38)
SCHEMBL1007315 0.79
SCHEMBL294588 0.78
SCHEMBL5373316 0.77
SCHEMBL49983 0.77 KIF11 (0.31)
SCHEMBL80520 0.77 KIF11 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110573013-B Plant disease control agent 明治制果药业株式会社 2021-10-29 CN disclosed
US-20210120817-A1 PLANT DISEASE CONTROL AGENT MEIJI SEIKA PHARMA CO., LTD. (JP) 2021-04-29 US disclosed
US-20200392107-A1 CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2020-12-17 US disclosed
EP-3747879-A1 CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF Toray Industries, Inc. (JP) 2020-12-09 EP disclosed
CN-110573013-A Plant disease control agent 明治制果药业株式会社 2019-12-13 CN disclosed
CN-105228974-A Ethylene oligomerization becomes the oligomerization process of the mixture of 1-hexene and 1-octene SASOL TECH PTY LTD 2016-01-06 CN disclosed
US-8633245-B2 PAI-1 inhibitor INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2014-01-21 US disclosed
EP-2272817-A1 PAI-1 INHIBITOR Institute of Medicinal Molecular Design, Inc. (JP) 2011-01-12 EP disclosed
US-20090312315-A1 PAI-1 INHIBITOR INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2009-12-17 US disclosed
US-7259155-B2 Phosphonic diester derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2007-08-21 US disclosed
US-7205409-B2 Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) ABBOTT LABORATORIES (US) 2007-04-17 US disclosed
US-20050256087-A1 Phosphonic acid diester compounds OTSUKA PHARMACEUTICAL FACTORY, INC. 2005-11-17 US disclosed
US-20050131019-A1 Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) ABBVIE INC. 2005-06-16 US disclosed
EP-0320733-B1 2-TERT.-BUTYL-5-ISOXAZOLYL METHYLTHIO-3(2H)-PYRIDAZIN-3-ONE DERIVATIVES BASF Aktiengesellschaft (DE) 1993-03-03 EP disclosed
US-4929617-A INSECTICIDES, MITICIDES BASF AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
EP-0351589-A2 3(2H)-Pyridazinone derivatives for controlling snails BASF Aktiengesellschaft (DE) 1990-01-24 EP disclosed
EP-0320733-A2 2-tert.-butyl-5-isoxazolyl methylthio-3(2H)-pyridazin-3-one derivatives BASF Aktiengesellschaft (DE) 1989-06-21 EP disclosed