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KIF11

Kinesin-like protein KIF11 · P52732 · KIF11 on Sugi Atlas →

161,757 patent compounds predicted against KIF11, 69,206 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL38315 SCHEMBL38315 1.00 20/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL34901) 0.96 20/20
SCHEMBL74609 SCHEMBL74609 0.88 20/20
SCHEMBL74610 SCHEMBL74610 0.88 20/20
SCHEMBL76162 SCHEMBL76162 0.88 20/20
SCHEMBL76163 SCHEMBL76163 0.88 20/20
SCHEMBL77150 SCHEMBL77150 0.88 20/20
SCHEMBL74153 SCHEMBL74153 0.86 20/20
SCHEMBL74154 SCHEMBL74154 0.86 20/20
SCHEMBL74667 SCHEMBL74667 0.86 20/20
SCHEMBL74019 SCHEMBL74019 0.80 20/20
SCHEMBL74020 SCHEMBL74020 0.80 20/20
SCHEMBL75785 SCHEMBL75785 0.80 20/20
SCHEMBL73657 SCHEMBL73657 0.79 20/20
SCHEMBL73658 SCHEMBL73658 0.79 20/20
SCHEMBL74131 SCHEMBL74131 0.79 20/20
SCHEMBL74556 SCHEMBL74556 0.79 20/20
SCHEMBL74074 SCHEMBL74074 0.78 20/20
SCHEMBL74075 SCHEMBL74075 0.78 20/20
SCHEMBL74155 SCHEMBL74155 0.77 20/20

Clinical trials — most relevant to KIF11 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Impact of tdrd9 Gene Mutations in the Therapeutic Response to L-carnitine in Oligoasthenozoospermic Men PHASE3ACTIVE_NOT_RECRUITING
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer PHASE2UNKNOWN
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype EARLY_PHASE1COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics nanCOMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Registry and Natural History of Epilepsy-Dyskinesia Syndromes nanRECRUITING
Exploring a Motor Learning Technique Based on the Mirror Motor Neuron System nanCOMPLETED
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN
Spastic Paraplegia - Centers of Excellence Research Network nanRECRUITING
Gait in Rare Diseases nanCOMPLETED
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases nanCOMPLETED
PCM1-JAK2 in Therapy Related Neoplasms nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay nanNOT_YET_RECRUITING
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases nanCOMPLETED
Better Delineation of BCL11B Related Phenotype and Epigenetic Signature. nanCOMPLETED
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome nanRECRUITING
Clinical Registry Investigating Bardet-Biedl Syndrome nanRECRUITING
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies nanRECRUITING
Gyrate Atrophy Ocular and Systemic Study nanACTIVE_NOT_RECRUITING
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Hong Kong Spinocerebellar Ataxias Registry nanRECRUITING
Early Detection and Characterization of Primary Ciliary Dyskinesia nanUNKNOWN
Structural Validity and Inter-rater Reliabitiliy of the Ataxia Trunk, Lower And Upper Extremity Scale (ATLAS) nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a KIF11 binder may also engage these)

ProteinNameSimilarity
Q91783 — 0.999 Q91783 →
Q6P9P6 — 0.998 Q6P9P6 →
Q9S7P3 — 0.997 Q9S7P3 →
F4IJK6 — 0.997 F4IJK6 →
O23826 — 0.996 O23826 →
Q7M6Z5 — 0.995 Q7M6Z5 →
P46863 — 0.995 P46863 →
Q86VH2 — 0.995 Q86VH2 →
F4IIS5 — 0.994 F4IIS5 →
Q2VIQ3 — 0.993 Q2VIQ3 →
P28025 — 0.993 P28025 →
F4J2K4 — 0.993 F4J2K4 →
B2GU58 — 0.992 B2GU58 →
F4IAR2 — 0.992 F4IAR2 →
Q8J1G4 — 0.992 Q8J1G4 →
Q8TDB6 — 0.992 Q8TDB6 →
B9FAF3 — 0.992 B9FAF3 →
KIF15 Kinesin-like protein KIF15 0.992 landscape →
Q90640 — 0.991 Q90640 →
Q60575 — 0.991 Q60575 →
Q9P0K7 — 0.991 Q9P0K7 →
Q9LZU5 — 0.991 Q9LZU5 →
Q91WD7 — 0.991 Q91WD7 →
Q8BMD7 — 0.991 Q8BMD7 →
Q91785 — 0.991 Q91785 →
Q94LW7 — 0.990 Q94LW7 →
Q12756 — 0.990 Q12756 →
Q80WE4 — 0.990 Q80WE4 →
Q9EQW7 — 0.990 Q9EQW7 →
Q6IVY4 — 0.989 Q6IVY4 →