Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26076630 | 0.85 | DPP4 (0.46) | CTSSCTSKAAK1PTPN1TRPA1 | |
| SCHEMBL268952 | 0.85 | PTPN1 (0.55) | SCN9ACTSSCTSKPTPN1 | |
| SCHEMBL268951 | 0.85 | PTPN1 (0.55) | SCN9ACTSSCTSKPTPN1 | |
| SCHEMBL10054499 | 0.85 | SCN9A (0.45) | SCN9ACTSSCTSKGPR119AAK1 | |
| SCHEMBL10054507 | 0.85 | SCN9A (0.45) | SCN9ACTSSCTSKGPR119AAK1 | |
| SCHEMBL1509242 | 0.85 | PTPN1 (0.55) | SCN9ACTSSCTSKPTPN1 | |
| SCHEMBL12849500 | 0.85 | SCN9A (0.45) | SCN9ACTSSCTSKGPR119AAK1 | |
| SCHEMBL269302 | 0.84 | CTSS (0.51) | SCN9ACTSSCTSKGPR119PTPN1 | |
| SCHEMBL6874637 | 0.84 | SCN9A (0.45) | SCN9ACTSSCTSKGPR119AAK1 | |
| SCHEMBL269301 | 0.84 | CTSS (0.51) | SCN9ACTSSCTSKGPR119PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |