Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074160 | 0.86 | DPP4 (0.36) | — | |
| SCHEMBL10077474 | 0.86 | ATM (0.40) | ATMCTSSCTSKSCN9AKLK5 | |
| SCHEMBL10074474 | 0.84 | ATM (0.43) | ATMCTSSCTSKSCN9AKLK5 | |
| SCHEMBL10074341 | 0.84 | ATM (0.43) | ATMCTSSCTSKSCN9AKLK5 | |
| SCHEMBL10078269 | 0.83 | ATM (0.41) | ATMCTSSCTSKSCN9AKLK5 | |
| SCHEMBL10077403 | 0.83 | ATM (0.41) | ATMCTSSCTSKSCN9AKLK5 | |
| SCHEMBL10074981 | 0.81 | ATM (0.41) | ATMCTSSCTSKSCN9AKLK5 | |
| SCHEMBL10074304 | 0.81 | ATM (0.41) | ATMCTSSCTSKSCN9AKLK5 | |
| SCHEMBL10078272 | 0.80 | KLK5 (0.40) | ATMCTSSCTSKSCN9AKLK5 | |
| SCHEMBL6872873 | 0.80 | ATM (0.48) | ATMCTSSCTSKSCN9AKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |