Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074277 | 0.88 | LAP3 (0.45) | DPP4DPP7DPP9LAP3ANPEP | |
| SCHEMBL10074161 | 0.86 | MMP2 (0.46) | DPP4DPP7DPP9LAP3ANPEP | |
| SCHEMBL10074490 | 0.86 | ATM (0.40) | — | |
| SCHEMBL10078080 | 0.84 | DPP4 (0.38) | DPP4DPP7DPP9LAP3ANPEP | |
| SCHEMBL10074349 | 0.74 | MMP2 (0.50) | DPP4DPP7DPP9LAP3ANPEP | |
| SCHEMBL10074145 | 0.74 | MMP2 (0.50) | DPP4DPP7DPP9LAP3ANPEP | |
| SCHEMBL10077474 | 0.72 | ATM (0.40) | ALDH1A1 | |
| SCHEMBL10077078 | 0.72 | LAP3 (0.45) | DPP4DPP7DPP9LAP3ANPEP | |
| SCHEMBL10078089 | 0.72 | LAP3 (0.45) | DPP4DPP7DPP9LAP3ANPEP | |
| SCHEMBL6873314 | 0.72 | LAP3 (0.49) | DPP4DPP7DPP9LAP3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |