Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003911 | 0.88 | KDM4E (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL713231 | 0.82 | MAPT (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL18515867 | 0.82 | KDM4E (0.41) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13465715 | 0.82 | MAPT (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL15497996 | 0.82 | MAPT (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13857478 | 0.81 | CHRM2 (0.35) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL31717069 | 0.79 | — | — | |
| SCHEMBL713948 | 0.78 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12510950 | 0.78 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8232821 | 0.78 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299463-B1 | ENZYMATIC ENCODING | NUEVOLUTION AS (DK) | 2020-10-21 | — | — | EP | disclosed |
| EP-2348125-B1 | Method for the synthesis of a bifunctional complex | NUEVOLUTION AS (DK) | 2017-06-21 | — | — | EP | disclosed |
| US-8206901-B2 | Method for the synthesis of a bifunctional complex | NUEVOLUTION A/S (DK) | 2012-06-26 | — | — | US | disclosed |
| EP-2348124-A2 | Synthesis of a bifunctional complex | Nuevolution A/S (DK) | 2011-07-27 | — | — | EP | disclosed |
| EP-2348125-A2 | Method for the synthesis of a bifunctional complex | Nuevolution A/S (DK) | 2011-07-27 | — | — | EP | disclosed |
| EP-1558744-B1 | ENZYMATIC ENCODING | NUEVOLUTION AS (DK) | 2011-06-15 | — | — | EP | disclosed |