Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074584 | 0.88 | KDM4E (0.39) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13465715 | 0.85 | MAPT (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL713231 | 0.85 | MAPT (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL15497996 | 0.85 | MAPT (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13160460 | 0.82 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1PLA2G2CMMP2MMP3 | |
| SCHEMBL713948 | 0.82 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5564073 | 0.82 | MMP2 (0.41) | MMP2MMP3MMP7TSHR | |
| SCHEMBL13154045 | 0.82 | CYP2C9 (0.39) | SMN1; SMN2ALDH1A1PLA2G2CMMP2MMP3 | |
| SCHEMBL890102 | 0.82 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1PLA2G2CMMP2MMP3 | |
| SCHEMBL12510950 | 0.82 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299463-B1 | ENZYMATIC ENCODING | NUEVOLUTION AS (DK) | 2020-10-21 | — | — | EP | disclosed |
| EP-2348125-B1 | Method for the synthesis of a bifunctional complex | NUEVOLUTION AS (DK) | 2017-06-21 | — | — | EP | disclosed |