Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 2/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077520 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10054406 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10078257 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10054396 | 0.91 | DPP4 (0.49) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10077069 | 0.91 | DPP4 (0.49) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10074146 | 0.91 | DPP4 (0.49) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10074723 | 0.89 | ITGB3 (0.47) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10077068 | 0.89 | ITGB3 (0.47) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10077056 | 0.88 | DPP4 (0.46) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10078256 | 0.88 | DPP4 (0.46) | DPP4DPP8DPP9DPP7ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |